Table 4.
Metabolite pathway changes between BSTSF and AD groups.
| No. | Pathway | Hits | Total | p | −Log(p) | FDR p | Impact |
|---|---|---|---|---|---|---|---|
| 1 | Alanine, aspartate, and glutamate metabolism | 2 | 28 | 0.0156 | 4.157 | 1 | 0.3101 |
| 2 | D-Glutamine and D-glutamate metabolism | 1 | 6 | 0.0419 | 3.1725 | 1 | 0 |
| 3 | Arginine biosynthesis | 1 | 14 | 0.0953 | 2.3509 | 1 | 0 |
| 4 | Glycosylphosphatidylinositol (GPI) anchor biosynthesis | 1 | 14 | 0.0953 | 2.3509 | 1 | 0.00399 |
| 5 | Nicotinate and nicotinamide metabolism | 1 | 15 | 0.1017 | 2.2851 | 1 | 0 |
| 6 | Histidine metabolism | 1 | 16 | 0.1082 | 2.2238 | 1 | 0 |
| 7 | Pantothenate and CoA biosynthesis | 1 | 19 | 0.1273 | 2.0615 | 1 | 0 |
| 8 | Beta-alanine metabolism | 1 | 21 | 0.1398 | 1.9678 | 1 | 0 |
| 9 | Cysteine and methionine metabolism | 1 | 33 | 0.2114 | 1.554 | 1 | 0.02089 |
| 10 | Glycerophospholipid metabolism | 1 | 36 | 0.2284 | 1.4765 | 1 | 0.10449 |
| 11 | Aminoacyl-tRNA biosynthesis | 1 | 48 | 0.2933 | 1.2265 | 1 | 0 |
Notes: hits represent the matched number of metabolites in one pathway. p represents the original p value calculated from the enrichment analysis. FDR p represents the p value adjusted using the false discovery rate.