Table 3.
Correlation analysis between inflammatory reaction in ALI induced by oleic acid and expression of key proteins in Wnt/β-catenin signaling pathway.
Index | ALI group | ALI + KGF-2 group | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Wnt5a | β-Catenin | APC | Wnt5a | β-Catenin | APC | ||||||||
r | P | r | P | r | P | r | P | r | P | r | P | ||
Inflammatory factor | TNF-α | 0.776 | 0.001 | 0.857 | 0.002 | 0.954 | 0.001 | 0.273 | 0.446 | 0.851 | 0.002 | 0.747 | 0.013 |
IL-10 | −0.879 | 0.001 | −0.830 | 0.03 | −0.697 | 0.025 | −0673 | 0.033 | −0.748 | 0.013 | −0.852 | 0.002 | |
Number of cells in BALF | White blood cell count | 0.888 | 0.001 | 0.827 | 0.003 | 0.063 | 0.037 | 0.298 | 0.403 | 0.957 | 0.001 | 0.907 | 0.001 |
Red blood cell count | 0.794 | 0.006 | 0.721 | 0.019 | 0.879 | 0.001 | 0.588 | 0.074 | 0.875 | 0.001 | 0.772 | 0.009 |
Note. TNF-α is tumor necrosis factor-α. IL-10 is interleukin-10. Wnt5a, β-catenin, and APC are key proteins in the Wnt/β-catenin signaling pathway. BALF is bronchoalveolar lavage fluid.