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Treatment Characteristics: Few Doses Tolerated Before Debilitating Disease Progression
| Total Doses | No. Patients |
|---|---|
| 1 | 3 |
| 2 | 8* |
| 3 | 4 |
| 4 (1 course) | 7† |
| 5 | |
| 6 | 2 |
| 7 | 1 |
| 8 (2 courses) | 2 |
| Grade 3 to 4 Immune-mediated adverse events | |
| Colitis | 1 |
| Hypophysitis | 1 |
| Encephalitis | 1 |
1 stopped for colitis, 1 stopped for encephalitis.
1 stopped for hypophysitis.
