Fig. 1.

(A) Timeline of the experiment. (B) The image depicts the course of cannula implantation. Guide cannulas were implanted, and L-AAA was infused through them (1.2 μl/mouse). (C) Location of L-AAA infusion. Guide cannula was aimed at the prefrontal cortex using the following coordinates: AP 1.7 mm, ML ±0.3 mm, and DV −2.5 mm from the bregma. FST, forced swimming test; L-AAA, L-alpha-aminoadipic acid; OFT, open-field test; TST, tail suspension test; AP, anterior-posterior; ML, medial-lateral; DV, dorsal-ventral.