Table 1.
Comparison of patient demographics in OPC samples selected for methylation data extraction; all samples in HN5000 identified as OPC and all samples in HN5000
| Variable | OPC in HN5000 with methylation data and complete phenotype data (N = 409) | OPC in HN5000 (N = 1909) | All HN5000 (all sub-types) (N = 5392) |
|---|---|---|---|
| ICD group (% oropharynx) | 100 | 100 | 35.4 |
| Sex (% female) | 27.0 | 21.9 | 27.2 |
| Age (% < 60) | 58.4 | 52.4 | 42.7 |
| Smoking (% never smoked) | 27.1 | 28.0 | 24.6 |
| Alcohol (% non-drinker) | 25.9 | 26.6 | 28.4 |
| HPV16 E6 (% negative) | 33.3 | 32.3 | 72.0 |
| Survival (% died, prior to 30/09/2017) | 26.2 | 24.2 | 28.0 |