Table 3.

Univariate analysis of 1-y NRM and 1-y OS

Variable	1-y NRM SHR (95% CI)	1-y OS HR (95% CI)
GA
Cognitive impairment by BOMC
<7	Reference	Reference
≥7	2.57 (1.34 to 4.95), P = .005*	1.56 (0.94 to 2.60), P = .09*
IADL
Normal (14)	Reference	Reference
Impaired (<14)	1.17 (0.69 to 2.06), P = .58	1.37 (0.95 to 1.97), P = .09*
Physical function by MOS-PH score
>80 (median score)	Reference	Reference
≤80	1.85 (0.94 to 3.61), P = .08*	1.26 (0.81 to 1.94), P = .30
TUG, s
<13.5	Reference	Reference
≥13.5	1.38 (0.64 to 2.99), P = .41	1.43 (0.86 to 2.38), P = .17
Clinical variables
Age, y
50 to 59	Reference	Reference
60 to 69	1.09 (0.56 to 2.10), P = .80	1.27 (0.83 to 1.93), P = .27
≥70	1.66 (0.77 to 3.59), P = .20	1.29 (0.75 to 2.22), P = .35
Karnofsky performance status
90 to 100	Reference	Reference
<90	1.31 (0.72 to 2.41), P = .38	1.40 (0.94 to 2.07), P = .1*
Comorbidity by HCT-CI
0 to 2	Reference	Reference
≥3	2.20 (1.22 to 3.97), P = .009*	1.28 (0.89 to 1.84), P = .18
DRI
Low, intermediate	Reference	Reference
High, very high	1.60 (0.87 to 2.93), P = .13	1.44 (0.97 to 2.13), P = .07*
Conditioning intensity
Myeloablative conditioning	Reference	Reference
Reduced intensity conditioning	1.48 (0.77 to 2.84), P = .24	1.43 (0.95 to 2.15), P = .09*
Donor type
Matched sibling	Reference	Reference
Other related	2.96 (1.02 to 8.59), P = .05	1.93 (0.85 to 4.35), P = .11
Well-matched unrelated; 8/8 match	1.29 (0.63 to 2.68), P = .49	1.18 (0.76 to 1.83), P = .46
Partially matched unrelated; 7/8 match	1.62 (0.57 to 4.63), P = .37	1.29 (0.65 to 2.54), P = .47
Cord blood	2.49 (1.08 to 5.76), P = .03	1.80 (1.03 to 3.15), P = .04
Across all donor types, by log rank	P = .14	P = .22
Graft source
Bone marrow	Reference	Reference
Peripheral blood	0.68 (0.27 to 1.72), P = .41	1.23 (0.60 to 2.53), P = .58
Umbilical cord blood	1.37 (0.47 to 3.97), P = .57	1.88 (0.82 to 4.30), P = .13

HCT-CI, hematopoietic cell transplant-comorbidity index.

^*Included in multivariate analysis since P ≤ .1.