Table 3.
Associations between replicated nutrition and lifestyle factors in relation to T deficiency in the discovery and replication datasets.
| Factors | Discovery dataset (NHANES III) | Replication dataset (NHANES 1999–2004) | |||||
|---|---|---|---|---|---|---|---|
| N = T deficiency | N = Total | OR (95% CI) | N = T deficiency | N = Total | OR (95% CI) | P-value | |
| Vitamin A intake (g) | 234 | 1273 | 0.90 (0.71–0.91 | 140 | 565 | 0.64 (0.46–0.89) | 0.01 |
| Protein intake (g) | 234 | 1273 | 0.67 (0.53–0.85 | 140 | 565 | 0.60 (0.45–0.81) | 0.003 |
| Saturated fatty acids intake (g) | 234 | 1273 | 0.71 (0.58–0.87) | 140 | 565 | 0.67 (0.51–0.89) | 0.01 |
| Monounsaturated fatty acids intake (g) | 234 | 1273 | 0.76 (0.64–0.89) | 140 | 565 | 0.68 (0.52–0.88) | 0.008 |
| Total fat intake (g) | 234 | 1273 | 0.75 (0.63–0.89) | 140 | 565 | 0.70 (0.54–0.91) | 0.01 |
| SFA 16:0 (g) | 234 | 1273 | 0.71 (0.58–0.88) | 140 | 565 | 0.68 (0.52–0.90) | 0.01 |
| Phosphate intake (mg) | 234 | 1273 | 0.70 (0.56–0.87) | 140 | 565 | 0.61 (0.42–0.87) | 0.01 |
All models were adjusted for age, BMI, race/ethnicity, education, PIR, SHBG and estradiol. Benjamini–Hochberg adjusted P-values for FDR < 5% are presented for the discovery dataset, and P-values from significance testing are presented for replication dataset.