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. Author manuscript; available in PMC: 2020 Jun 29.
Published in final edited form as: Hormones (Athens). 2020 Feb 19;19(2):205–214. doi: 10.1007/s42000-020-00179-w

Table 3.

Associations between replicated nutrition and lifestyle factors in relation to T deficiency in the discovery and replication datasets.

Factors Discovery dataset (NHANES III) Replication dataset (NHANES 1999–2004)
N = T deficiency N = Total OR (95% CI) N = T deficiency N = Total OR (95% CI) P-value
Vitamin A intake (g) 234 1273 0.90 (0.71–0.91 140 565 0.64 (0.46–0.89) 0.01
Protein intake (g) 234 1273 0.67 (0.53–0.85 140 565 0.60 (0.45–0.81) 0.003
Saturated fatty acids intake (g) 234 1273 0.71 (0.58–0.87) 140 565 0.67 (0.51–0.89) 0.01
Monounsaturated fatty acids intake (g) 234 1273 0.76 (0.64–0.89) 140 565 0.68 (0.52–0.88) 0.008
Total fat intake (g) 234 1273 0.75 (0.63–0.89) 140 565 0.70 (0.54–0.91) 0.01
SFA 16:0 (g) 234 1273 0.71 (0.58–0.88) 140 565 0.68 (0.52–0.90) 0.01
Phosphate intake (mg) 234 1273 0.70 (0.56–0.87) 140 565 0.61 (0.42–0.87) 0.01

All models were adjusted for age, BMI, race/ethnicity, education, PIR, SHBG and estradiol. Benjamini–Hochberg adjusted P-values for FDR < 5% are presented for the discovery dataset, and P-values from significance testing are presented for replication dataset.