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Trace elements in cell supernatants were determined using flame atomic absorption spectrometry, compared with the LOVO, *, P<0.05; **, P < 0.01 (a); compared with the LOVO+NFs, #, P < 0.05; ##, P < 0.01. LOXL2 expression levels were determined in co-culture models (b). Compared with the NFs, *, P < 0.05; **, P < 0.01.
NFs, normal fibroblasts.
