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. 2020 Jul 28;190(4):520–524. doi: 10.1111/bjh.16938

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© 2020 British Society for Haematology and John Wiley & Sons Ltd

This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

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Fig 1 — (A) Cytoscape rendering of SERPING1 interactions retrieved from BioGrid. Viral proteins are in red, contact system and coagulation factors in dark blue. (B) Similarities between CoV‐1 and CoV‐2 proteins, estimated from pairwise alignments (Supporting Information). (C) Cytoscape rendering of the nodes with the highest connectivity of human proteins with CoV‐1 and CoV‐2 proteins, merged from BioGrid interaction networks (https://thebiogrid.org). SERPING1 is shown in orange and edges of its interactions with CoV‐1 proteins are in red. Viral proteins are in red; innate immunity and interferon pathway components are in yellow.