Table 1.
Baseline characteristics of the study cohort.
| Female N=178 | Male N=391 | P | |
|---|---|---|---|
| Age | 50.3 ± 13.9 | 52.4 ± 12.1 | 0.1 |
| Race | 0.032 | ||
| • White | 61 (34.3) | 178 (45.5) | |
| • Black | 109 (61.2) | 198 (50.6) | |
| • Hispanic | 3 (1.7) | 2 (0.5) | |
| • Asian | 1 (0.6) | 8 (2.0) | |
| • Unknown | 4 (2.2) | 5 (1.3) | |
| Insurance | 0.6 | ||
| • Private | 83 (46.6) | 199 (50.9) | |
| • Medicare | 73 (41.0) | 149 (38.1) | |
| • Medicaid | 22 (12.3) | 42 (10.7) | |
| Heart failure type | <0.0001 | ||
| • Ischemic | 26 (14.6) | 127 (32.5) | |
| • Nonischemic | 99 (55.6) | 223 (57.0) | |
| • Peripartum | 25 (14.0) | 0 (0.0) | |
| • Restrictive | 2 (1.1) | 0 (0.0) | |
| • Other | 21 (11.8) | 31 (7.9) | |
| • ACHD | 5 (2.8) | 10 (2.6) | |
| Coronary artery disease | 56 (31.5) | 204 (52.2) | <0.0001 |
| Lung disease | 27 (15.2) | 44 (11.3) | 0.2 |
| Diabetes mellitus | 57 (32.0) | 140 (35.8) | 0.4 |
| Hypertension | 83 (46.6) | 257 (65.7) | <0.0001 |
| CKD categories • Stage 1–2 • Stage 3 • Stage 4–5 |
73 (41) 85 (47.8) 20 (11.2) |
184 (47.1) 173 (44.2) 34 (8.7) |
0.3 |
| Left ventricular thrombus | 23 (12.9) | 56 (14.3) | 0.7 |
| Inotropes at discharge | 105 (59.0) | 251 (64.2) | 0.2 |
| PRA Class I | 46.8 ± 28.8 | 26.0 ± 24.5 | 0.1 |
| PRA Class II | 56.2 ± 26.4 | 28.7 ± 20.7 | 0.5 |
| Allosensitization (PRA >10%) | 79 (51.6) | 33 (10.2) | <0.0001 |
| Body mass index (kg/m2) | 29.8 ± 7.6 | 28.9 ± 6.6 | 0.2 |
| Body mass index categories • <18 • 18–24.9 • 25–29.9 • 30–34.9 • ≥35 |
3 (1.7) 53 (30.3) 48 (27.4) 30 (17.1) 41 (23.4) |
5 (1.3) 107 (27.6) 133 (34.3) 87 (22.4) 56 (14.4) |
0.05 |
| Right atrial pressure (mmHg) | 12.6 ± 6.5 | 12.0 ± 6.5 | 0.4 |
| Mean pulmonary artery pressure (mmHg) | 36.6 ± 11.0 | 36.0 ± 11.1 | 0.6 |
| Pulmonary capillary wedge pressure (mmHg) | 24.9 ± 9.7 | 25.2 ± 9.7 | 0.7 |
| Cardiac output (L/min) | 3.2 ± 1.0 | 3.8 ± 1.1 | <0.0001 |
| Cardiac index (L/min/m2) | 1.8 ± 0.6 | 1.9 ± 1.1 | 0.4 |
| Hematocrit (%) | 35.4 ± 4.8 | 37.5 ± 6.1 | <0.0001 |
| Hemoglobin A1C (%) | 6.4 ± 1.1 | 6.5 ± 1.5 | 0.6 |
| Total bilirubin (mg/dL) | 1.4 ± 1.2 | 1.7 ± 1.3 | 0.020 |
| Sodium (mmol/L) | 135.2 ± 4.2 | 134.5 ± 5.1 | 0.1 |
| Blood urea nitrogen (mg/dL) | 26.2 ± 17.1 | 30.1 ± 20.0 | 0.027 |
| Creatinine (mg/dL) | 1.3 ± 0.5 | 1.6 ± 0.8 | <0.0001 |
| Estimated glomerular filtration rate (ml/min/1.73 m2) | 56.1 ± 22.7 | 60.5 ± 24.4 | 0.044 |
| Albumin (g/dL) | 3.5 ± 0.6 | 3.4 ± 0.6 | 0.7 |
Values are mean ± standard deviation, N(%), or median (interquartile range).