Table 6.
IgA Threshold, U/mL | n (%) | Any Severity of Rotavirus Gastroenteritis | Severe Rotavirus Gastroenteritis | ||||||
---|---|---|---|---|---|---|---|---|---|
Events, n (%) | Time at Risk, wk | Cumulative Hazard per 100 (95% CI) | HRa (95% CI) | Events, n (%) | Time at Risk, wk | Cumulative Hazard per 100 (95% CI) | HRa (95% CI) | ||
Very low child mortality (any severity n = 1733; severe n = 1704) | |||||||||
Seronegative | 306 (17.7) | 6 (0.3) | 7958 | 2.74 (.28–5.20) | 1.00 (ref) | 1 (0.1) | 7825 | 0.34 (.00–1.01) | 1.00 (ref) |
≥20 | 1427 (82.3) | 3 (0.2) | 37 742 | 0.33 (.00–.74) | 0.11 (.03–.42) | 0 (0.0) | 37 218 | 0.00 (NA) | 0.00 (NA) |
Moderately low child mortality (any severity n = 815; severe n = 777) | |||||||||
Seronegative | 269 (33.0) | 16 (2.0) | 7228 | 6.45 (3.29–9.62) | 1.00 (ref) | 10 (1.3) | 6852 | 4.20 (1.60–6.80) | 1.00 (ref) |
≥20 | 546 (67.0) | 8 (1.0) | 15 107 | 1.59 (.48–2.69) | 0.25 (.11–0.59) | 1 (0.1) | 14 595 | 0.19 (.00–.57) | 0.05 (.01–.41) |
Abbreviations: CI, confidence interval; HR, hazard ratio; IgA, antirotavirus immunoglobulin A; NA, not applicable.
aModels include study as a frailty term.