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. 2020 Jul;26(7):1478–1488. doi: 10.3201/eid2607.200841

Table 3. Correlations between ODs/OD ratios and PRNT results of 10 serum samples obtained from 3 PCR-confirmed COVID-19 patients from France and tested in Rotterdam, the Netherlands, 6–27 d after diagnosis*.

Test, virus Correlations In-house ELISAs
Euroimmun ELISAs
S1 N RBD S S1A IgA IgG
PRNT50, SARS-CoV-2
Spearman ρ value 0.87 0.94 0.92 0.94 0.93 0.98 0.92
2-tailed p value 0.0021 0.0002 0.0005 0.0002 0.0003 <0.0001 0.0005
p value summary
<0.01
<0.001
<0.001
<0.001
<0.001

<0.0001
<0.001
PRNT90, SARS-CoV-2 Spearman ρ value 0.88 0.88 0.88 0.88 0.88 0.93 0.88
2-tailed p value 0.0024 0.0024 0.0024 0.0024 0.0024 0.0008 0.002
p value summary <0.01 <0.01 <0.01 <0.01 <0.01 <0.001 <0.01

*COVID-19, coronavirus disease 2019; OD, optical density; N, nucleocapsid; PRNT50, 50% plaque reduction neutralization test; PRNT90, 90% plaque reduction neutralization test; RBD, receptor-binding domain; S, spike; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.