Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jun 18;11:524. doi: 10.3389/fneur.2020.00524

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Rajan, Divya, Kandadai, Yadav, Satagopam, Madhusoodanan, Agarwal, Kumar, Ferreira, Kumar, Sreeram Prasad, Shetty, Mehta, Desai, Kumar, Prashanth, Bhatt, Wadia, Ramalingam, Wali, Pandey, Bartusch, Hannussek, Krüger, Kumar-Sreelatha, Grover, Lichtner, Sturm, Roeper, Busskamp, Chandak, Schwamborn, Seth, Gasser, Riess, Goyal, Pal, Borgohain, Krüger, Kishore, Sharma and the Lux-GIANT Consortium.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Overall flow chart describing the details of the Lux-GIANT consortium. The consortium follows the “hub-spoke” model. The Lux-GIANT has established three main cores: genomics, clinical, and functional genomics. The University of Tubingen is the coordinator site. Luxembourg site aims to strengthen functional genomics and system biology. Functional core from India, National Brain Research Center, will be responsible for developing and maintaining iPSCs. Four main clinical-nodes capturing most of India are formed. These four nodes are connected to clinical sub-centers which span throughout India. The “central clinical node” aims to streamline the administrative process, which is required for clearance and sample shipment. The different nodes within India are connected with the main “central clinical node” for continuous update of cohort and members.