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Parameters of alarmone interaction with XPRT
| Kd (μM) | nH | IC50 (μM) | napp | |
|---|---|---|---|---|
| pppGpp | 9.6 ± 2.2 | 1.3 ± 0.2 | 56.4 ± 1.8 | 1.5 ± 0.1 |
| ppGpp | 0.95 ± 0.03 | 2.1 ± 0.1 | 3.3 ± 0.1 | 1.7 ± 0.1 |
| pGpp | 0.76 ± 0.04 | 2.3 ± 0.2 | 0.96 ± 0.04 | 1.6 ± 0.1 |
IC50 = half maximal inhibitory concentration
nH = Hill coefficient from binding curve
napp = apparent Hill coefficient from inhibition curve
± standard error
