Table 2.
Incidence of ordinal PS among male offspring evaluated at PNW 11–12 for each dose group (Saillenfait et al., 2008).
| Dose (mg/kg-da) | Total Litters Examined | Total Males Examined | Incidenceb |
|||
|---|---|---|---|---|---|---|
| Level 0 | Level 1 | Level 2 | Levels 1 & 2 | |||
| 0 | 12 | 24 | 24 (100%) | 0 (0%) | 0 (0%) | 0 (0%) |
| 125 | 10 | 20 | 18 (90%) | 1 (5%) | 1 (5%) | 2 (10%) |
| 250 | 14 | 28 | 21 (75%) | 6 (21%) | 1 (4%) | 7 (75%) |
| 500 | 11 | 22 | 5 (23%) | 9 (41%) | 8 (36%) | 17 (77%) |
| 625 | 10 | 20 | 0 (0%) | 3 (15%) | 17 (85%) | 20 (100%) |
a
“mg/kg-d” = mg/kg-day.
b
Ordinal levels 0, 1, and 2 are described in Section 2.2.