Table 1.

Association Between miR-512-3p Expression and Clinicopathologic Features of Patients with Hepatocellular Carcinoma

Characteristics	Number (n=45)	miR-512-3p Levels		P-value
		High (n=23)	Low (n=22)
Age (years)				0.292
<60	15	6	9
≥60	30	17	13
Gender				0.445
Male	33	18	15
Female	12	5	7
HBV infection				0.654
Negative	9	4	5
Positive	36	19	17
Liver cirrhosis				0.150
Absent	12	4	8
Present	33	19	14
AFP (ng/mL)				0.666
<20	11	5	6
≥20	34	18	16
Tumor size				0.026*
<5cm	21	7	14
≥5cm	24	16	8
Tumor multiplicity				0.608
Single	29	14	15
Multiple	16	9	7
Vascular invasion				0.042*
No	28	11	17
Yes	17	12	5
Edmondson–Steiner grade				0.399
Ⅰ+Ⅱ	30	14	16
III+Ⅳ	15	9	6
TNM stage				0.009*
Ⅰ+Ⅱ	33	13	20
III+Ⅳ	12	10	2

Note: *P<0.05, statistically significant difference.

Abbreviations: HBV, hepatitis B virus; AFP, alpha-fetoprotein; TNM, tumor-node-metastasis.