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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: J Immunol. 2020 Apr 13;204(11):2961–2972. doi: 10.4049/jimmunol.1901136

Figure 7.

Figure 7.

CD8+ T cell recruitment is significantly impaired in STING-deficient tumors A) Tumors were taken on day 5 and imaged for the presence of CD8+ T cells. B) B6 + PBS (n=2 tumors, 5–8 images per tumor), B6 + MCMV (n=3 tumors, 6–8 images per tumor), STING-def +PBS (n=1 tumor, 8 images per tumor, from STINGgt/gt only), STING-def + MCMV(n=3 tumors, 6–8 images per tumor, from STINGgt/gt only) tumor images were quantified to generate CD8 numbers per mm2 image by counting CD8+CD45.2+CD11b- cells with clear DAPI staining. In all cases, significance was determined using a Mann-Whitney test, **** p <0.0001.