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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Reprod Toxicol. 2020 May 17;95:95–103. doi: 10.1016/j.reprotox.2020.05.006

Table 2.

Effects of in utero exposure to arsenic on fertility of adult males.

Treatment Days to 1st litter Average days between litters Average number of pups per litter Average number of litters per female Total number of pups per female

Control 21 ± 0.3 27 ± 1.6 13 ± 0.4 6 ± 0 76 ± 3.9
10 ppb 21 ± 0.4 29 ± 1.6 14 ± 0.4 5 ± 0.4 70 ± 6.0
42.5 ppm 22 ± 0.4 31 ± 1.8 12 ± 0.6 5 ± 0.5 55 ± 6.3 *

Exposed males were mated with normal females that were not exposed to arsenic. Breeding began at 8 weeks of age and continued for 6 months. Numbers represent mean ± SEM. Significant differences from control are indicated by an asterisk (P < 0.05, control: n = 6; 10 ppb: n = 6; 42.5 ppm: n = 6).