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. 2020 Jun 25;181(7):1502–1517.e23. doi: 10.1016/j.cell.2020.05.035

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© 2020 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Figure S3 — IAV mRNAs Can Be Translated from Host-Derived AUGs, Related to Figure 3

(A) Length distribution of ribosome profiling reads that aligned to human (left panel) and viral (right panel) transcripts in DMSO (Ribo) or harringtonine (Ribo + Harr) treated samples.

(B) Metagene alignment of average P site density around annotated start codons in human (left panel) or viral (right panel) transcripts in DMSO treated samples.

(C) Metagene alignment of average P site density around annotated start codons in human (left panel) or viral (right panel) transcripts in harringtonine treated samples.

(D) Frequency of AUG codons by position relative to the viral transcription initiation site. Bars show the mean frequency and are color coded according to frame. Error bars indicate the standard deviation.