Table 4. Treatment-related complications in patients with surgically resected non-small cell lung cancer with or without idiopathic pulmonary fibrosis.
(A) Surgery-related complications | |||
LC with IPF (n = 96) | LC without IPF (n = 192) | P-value | |
Pneumonia | 11 (11.5) | 25 (13.0) | 0.706 |
Pneumothorax | 20 (20.8) | 24 (12.0) | 0.509 |
BPF | 1 (1.0) | 2 (1.0) | 1.000 |
Prolonged MV | 2 (2.1) | 10 (5.2) | 0.224 |
Arrythmia | 1 (1.0) | 2 (1.0) | 1.000 |
Bleeding | 2 (2.1) | 3 (1.6) | 0.751 |
ARDS* | 2 (2.1) | 2 (1.0) | 0.255 |
AE–IPF | 5 (5.2) | – | |
ARDS or AE–IPF | 7 (7.3) | 2 (1.0) | 0.012 |
(B) Adjuvant treatment-related complication (n = 110) | |||
Postoperative hospital day | 10.2 ± 10.0 | 9.8 ± 11.9 | 0.780 |
LC with IPF (n = 30) | LC without IPF (n = 80) | P-value | |
Cytopenia | 2 (6.7) | 17 (21.2) | 0.091 |
GI trouble | 8 (26.7) | 28 (35.0) | 0.409 |
Pneumonia | 6 (20.0) | 6 (7.5) | 0.071 |
Pneumonitis | 1 (3.4) | 1 (1.2) | 0.469 |
AE–IPF | 2 (6.7) | 0 (0.0) | 0.126 |
Values are expressed as number (%).
*ARDS other than AE-IPF
AE-IPF, acute exacerbation of idiopathic pulmonary fibrosis; ARDS, acute respiratory distress syndrome; BPF, bronchopleural fistula; GI, gastrointestinal; LC, lung cancer; MV, mechanical ventilation