(A–N) Families DSPD-1, -2, -4, -6, -7, -9, -14, -31, -34, -51, -52, -53, -58, and -59 underwent psychiatric evaluation during personal interviews and using sleep and ChronoType questionnaires (1, 21, 22). Individual ID numbers followed by DSM-5 scores and the MSF are shown below and the genotype status (+ denotes the WT allele; C denotes the mutant allele) in the pedigree symbols. See Supplemental Tables 1–3 for further details.