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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: J Immunol. 2020 Mar 20;204(9):2360–2373. doi: 10.4049/jimmunol.2000028

Figure 5. Lung infiltrates and effector memory T cells are increased in CopaE241K/+ host mice.

Figure 5.

A. Representative H&E stain of the lungs from bone marrow chimeras. Scale bar: 500 μM.

B. Disease scores of lung sections from bone marrow chimeras after 8 weeks of reconstitution (WT→WT, n = 3; WT→HET, n = 6; HET→WT, n = 6; HET→HET, n = 3).

C. left: Flow plots showing the expression of CD62L and CD44 on reconstituted splenic T cells. right: Percentages of effector memory T cell populations among the reconstituted T cells (6–8 weeks of reconstitution) in spleen (WT→WT, n = 7; WT→HET, n = 8; HET→WT, n = 8; HET→HET, n = 5).

Data are mean ± SD. Mann–Whitney U test was used in B. p < 0.05 is considered statistically significant. ns: not significant. A taken at 2x magnification, scale bar = 50μm.