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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: J Immunol. 2020 Mar 20;204(9):2360–2373. doi: 10.4049/jimmunol.2000028

Figure 6. Mutant Copa in the thymic stroma causes increased single positive thymocytes.

Figure 6.

A. top: Schedule from fetal thymus organ culture (FTOC) to transplantation to analysis. bottom: An image of grafted thymi.

B. left: CD4 and CD8 profile of thymocytes in transplanted thymi. right: Percentages of CD4SP and CD8SP (WT, n = 4; HET, n = 4).

C. left: CD69 and TCRβ profile of thymocytes in transplanted thymi. right: Percentages of TCRβ+CD69+ and TCRβ+CD69- thymocytes (WT, n = 4; HET, n = 4).

Data are mean ± SD. Unpaired, parametric, two-tailed Student’s t-test was used for statistical analysis. p < 0.05 is considered statistically significant. ns: not significant.