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. 2020 Jun 29;10:10568. doi: 10.1038/s41598-020-66716-0

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Panels (a), (b), and (c) depict the gridline schematic on NPM1 and NPM2, that is used to extract the deposition fractions from the gamma scintigraphy-based quantification of the sprayed deposits in the solid replicas. The models are respectively segregated into 3 sets of compartments: sagittal columns, frontal columns, and sagittal rows. Panel (d) shows the perturbation of the base gridline by 1 pixel. Representative Technetium signals are in panel (e). Note: In regard to the axis system, the circle with solid dot implies out-of-plane direction from this page, the circle with cross signifies into-the-plane of this page.