Table 3.
Multivariate survival analyses with the overall survival time for (A) THRα1 expression in the nucleus, (B) THRα2 expression in the cytoplasm, regarding patients age, histological subtype, grading, and staging (n = 146)
| Variables | p value | Hazard ratio | 95.0% Confidence Interval | |
|---|---|---|---|---|
| Lower | Upper | |||
| (A) THRα1 (nucleus) | ||||
| IRS > 0 versus IRS 0 | 0.049 | 0.618 | 0.383 | 0.997 |
| FIGO | ||||
| I/II versus III/IV | 0.001 | 2.761 | 1.510 | |
| Grading | ||||
| G1/low grade versus | 0.002 | 2.753 | 1.457 | 5.199 |
| G2/3/high grade | ||||
| Histological subtype | ||||
| all subtypes versus high-grade serous | 0.964 | 0.994 | 0.783 | 1.263 |
| Age | ||||
| < 60 versus ≥ 60 years | 0.116 | 0.717 | 0.473 | 1.085 |
| (B) THRα2 (cytoplasm) | ||||
| IRS > 0 versus IRS 0 | 0.002 | 2.790 | 1.466 | 5.310 |
| Age | ||||
| < 60 versus ≥ 60 years | 0.212 | 0.769 | 0.509 | 1.161 |
| Histological subtype | ||||
| all other subtypes versus high-grade serous | 0.673 | 0.950 | 0.747 | 1.207 |
| Grading | ||||
| G1/low-grade versus | 0.001 | 0.325 | 0.171 | 0.618 |
| G2/3/high-grade | ||||
| FIGO | ||||
| I/II versus III/IV | 0.001 | 0.365 | 0.201 | 0.662 |