Overview of the current understanding of the prognostic value of different immune subsets at different HNSCC subsites. Green indicates > 50% of papers report positive correlation, red indicates > 50% of papers report negative correlation and yellow indicates > 50% of papers report no correlation, or number of studies reporting opposite effects are equal. Size represents amount of papers considered. Small 0–5 papers; medium 6–10 papers; large > 10 papers. Abbreviations: HPV, human papillomavirus; NK cells, natural killer cells; mDC, myeloid dendritic cells; pDC, plasmacytoid dendritic cells; MDSC, myeloid derived suppressor cells; Tregs, regulatory T-cells; Bregs, regulatory B-cells