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. 2020 Apr 12;33(3):599–609. doi: 10.1007/s13577-020-00332-y

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Cell viability of various hematologic neoplastic cells in response to the KNT cell-conditioned medium (CM). The green line represents the control (n = 3). CM from young KNT cells [red lines, (n = 3): KNT_D_170714 and KNT_L_170714] inhibited the growth of the lymphoma and myeloma cell lines, but enhanced the growth of the leukemia cell lines. The blue line shows the response to CM from elderly KNT cells [blue lines, (n = 3): KNT_80_170825 and KNT_86_170825]. Values are means ± SD of three independent experiments, with each performed on different days