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Corneal swelling and lactate efflux in de-epithelialized (De-epi) rabbit corneas. (A) Change in CT (ΔCT) over time in GBR and effects of changing endothelial perfusion (at arrow) to 100 µM Ouabain, 100 µmol/L ACTZ, and BF Ringers. (B) Lactate content in perfusate collected over 30-minute intervals. (C) Total lactate efflux over the 120- to 300-minute period. (D) [Lactate] in corneas at end of the experiment (n = 3 corneas per condition).
