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CT and lactate flux in de-epithelialized preswollen corneas. (A) Change in CT (ΔCT) over time in GBR and effects of changing endothelial perfusion (at arrow) to 100 µM Ouabain, 100 µM ACTZ, and BF Ringers. (B) Lactate content in perfusate collected over 30-minute intervals. (C) Total lactate efflux over the 120- to 300-minute period. (D) [Lactate] in cornea at end of experiment (n = 3 corneas per condition).
