Table 2.

Selected genes with pro-oncogenic associations that are down-regulated in BHT-101 ASH1L KO cells^a

Gene symbol	Gene name	FDR	Rank by FDR	Log2 FC	Rank by fold repression
HAPL1	Hyaluronan and proteoglycan link protein 1	1.76 × 10−10	5	−5.08	5
MORC4	MORC family CW-type zinc finger 4	7.18 × 10−8	7	−2.14	23
CCAT1	Colon cancer associated transcript 1	7.52 × 10−5	11	−6.10	2
NNMT	Nicotinamide N-methyltransferase	8.76 × 10−5	12	−2.88	14
TWSG1	Twisted gastrulation BMP signaling modulator 1	2.48 × 10−4	14	−1.60	42
TRIB3	Tribbles pseudo-kinase 3	3.60 × 10−4	15	−1.66	39
IL6	Interleukin 6	0.0013	22	−1.87	31
PRDM9	PR/SET domain 9	0.0069	35	−4.37	8

^a Genes are sorted by FDR.