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. 2020 May 8;295(26):8798–8807. doi: 10.1074/jbc.RA120.012781

Figure 6.

Figure 6.

Model of the roles of Hippo pathway in VGLL3-low or -high cells. A, Hippo pathway–mediated inactivation of YAP/TAZ represses cell proliferation through inhibition of TEAD-dependent gene expression (CTGF etc.) in VGLL3-low cells. B, Hippo pathway-mediated inactivation of YAP/TAZ facilitates association of VGLL3 with TEAD and then promotes cell proliferation through TEAD-dependent gene expression in VGLL3-high cells.