TABLE 4.

Predicted miRNA response elements of top five upregulated and downregulated circRNAs.

CircRNA ID	Predicted miRNA response elements (MREs)
	MRE1	MRE2	MRE3	MRE4	MRE5
Upgraduated
hsa_circRNA_001145	hsa-miR-296-5p	hsa-miR-1226-5p	hsa-miR-6887-3p	hsa-miR-7106-3p	hsa-miR-6508-3p
hsa_circRNA_101138	hsa-miR-376b-3p	hsa-miR-376a-3p	hsa-miR-513a-5p	hsa-miR-103a-3p	hsa-miR-107
hsa_circRNA_030050	hsa-miR-29b-1-5p	hsa-miR-7161-3p	hsa-miR-6868-3p	hsa-miR-142-3p	hsa-miR-19b-2-5p
hsa_circRNA_061570	hsa-miR-6770-3p	hsa-miR-3934-3p	hsa-miR-4448	hsa-miR-4642	hsa-miR-6740-3p
hsa_circRNA_401117	hsa-miR-4677-5p	hsa-miR-6733-3p	hsa-miR-199a-5p	hsa-miR-578	hsa-miR-657
Downgraduated
hsa_circRNA_005537	hsa-miR-5009-5p	hsa-miR-6512-5p	hsa-miR-4753-3p	hsa-miR-6738-3p	hsa-miR-4760-3p
hsa_circRNA_092522	hsa-miR-3690	hsa-miR-615-5p	hsa-miR-422a	hsa-miR-1298-5p	hsa-miR-7641
hsa_circRNA_012989	hsa-miR-6792-3p	hsa-miR-8069	hsa-miR-4691-5p	hsa-miR-107	hsa-miR-103a-3p
hsa_circRNA_005458	hsa-miR-5708	hsa-miR-4701-3p	hsa-miR-765	hsa-miR-4522	hsa-miR-513a-5p
hsa_circRNA_050545	hsa-miR-6817-5p	hsa-miR-3170	hsa-miR-4769-3p	hsa-miR-4686	hsa-miR-513b-3p