Figure 3.

Local lung ferritin and iron levels do not correlate with systemic markers of iron storage or inflammation. (A) Haemoglobin (g/dL) and (B) CRP (μg/mL) levels in never-smokers (n = 25,20, red), ever-smokers without COPD (n = 85,44, blue) and ever-smokers with COPD (n = 83,55, green), as previously measured using a Luminex-based multiplex assay system⁶² and association with BALF ferritin (ng/mL), BALF iron (μg/L), and plasma ferritin (ng/mL) were tested with a linear model on the log-transformed markers and accounting for batch and site effects. $\hat{\beta }$ denotes adjusted increase in log-10 ferritin associated with unit increase in log-10 marker.