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. 2020 Jun 29;10:10576. doi: 10.1038/s41598-020-67522-4

Figure 6.

Figure 6

In vivo application of the HA-pep3. (a) Viability of Saos-2 cells treated with HA-pep3. (b) In vivo fluorescence imaging of BALB/c nude mice at 3 and 6 h after intravenous injection of Cy5.5-scramble peptide and Cy5.5-HA pep3. Skin, skull, spine, and joint are marked as dashed lines. (c) Ex vivo fluorescence imaging of bone and major tissues using the HA-pep3 and scramble peptide. (d) Fluorescence signal intensity graph of HA-pep3 and scramble peptide in bone and major tissues.