Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jun 23;11:1069. doi: 10.3389/fimmu.2020.01069

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Li, Chen, Ji, Sun, Jin, Jin, Sun, Zeng, Zhang, Lu, Luo, Zhao, Luo, Zou and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Specific IgG and IgG subclasses profiles of mice immunized with either of the AbOMVs. BALB/c mice were immunized intramuscularly or intranasally with SuOMV, sOMV, or nOMV. The serum was collected every week until the time of challenge. (A,B) Specific serum IgG antibody titers were measured by ELISA. (C,D,F,G) The levels of specific IgG1 and IgG2a in serum samples were tested. (E,H) The IgG2a/IgG1 ratio (ratios>1 and <1 indicate a Th1 and Th2 polarized response, respectively). Data are expressed as mean ± S.D., n = 10. **P < 0.01, ***P < 0.001, ****P < 0.0001, compared with PBS control.