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. 2020 Jun 23;11:1182. doi: 10.3389/fimmu.2020.01182

Figure 4.

Figure 4

Main tolerogenic mechanisms of the Th3 regulatory T cell. Th3 regulatory T cells suppress in a cell-contact independent mechanism only by the production of TGF-β, IL-10 and differ here from the Tr1 regulatory T cell by the production of IL-4. TGF-β, transforming growth factor-beta; IL, interleukin.