TABLE 3.
PTV and OARs parameters for MCO auto and clinical manual plans. In bold the P‐values expressing a statistically significant difference between auto and manual plan at the 0.05 level.
| PTV V95% (%) | PTV D0.1 cm 3 (Gy) | GI | PCI | Chest wall V30 Gy (%) | Total lung V20 Gy (%) | Heart D0.5 cm 3 (Gy) | Esophagus D0.5 cm 3 (Gy) |
Cord D0.1 cm 3 (Gy) |
Cord D1 cm 3 (Gy) | |
|---|---|---|---|---|---|---|---|---|---|---|
| MCO MFS auto plan (AVG ± 1SD) | 98.1 ± 1.2 | 59.5 ± 0.4 | 5.0 ± 0.6 | 0.83 ± 0.08 | 20.0 ± 12.3 | 5.2 ± 3.0 | 9.7 ± 7.6 | 8.7 ± 5.7 | 8.7 ± 4.5 | 8.0 ± 4.0 |
| MCO HFS auto plan (AVG ± 1SD) | 98.0 ± 2.0 | 59.6 ± 0.4 | 5.0 ± 0.7 | 0.75 ± 0.14 | 21.5 ± 12.5 | 5.4 ± 3.0 | 11.0 ± 8.1 | 9.5 ± 4.5 | 8.7 ± 4.3 | 7.8 ± 4.0 |
|
Clinical plan (AVG ± 1SD) |
97.5 ± 1.9 | 58.7 ± 2.5 | 6.6 ± 1.4 | 0.77 ± 0.12 | 26.4 ± 14.0 | 6.2 ± 3.2 | 11.8 ± 9.3 | 10.4 ± 3.5 | 10.7 ± 4.3 | 9.1 ± 4.1 |
| p MCO MFS vs clinical | 0.3 | 0.1 | <0.01 | 0.02 | <0.01 | <0.01 | 0.2 | 0.06 | <0.01 | 0.07 |
| p MCO HFS vs clinical | 0.2 | 0.07 | <0.01 | 0.7 | 0.03 | <0.01 | 0.2 | 0.2 | <0.01 | 0.03 |
MFS, Medium Fluence Smoothing; HFS, High Fluence Smoothing; OARs, organs at risk; PTV, planning target volume; V95%, volume receiving 95% of the prescription isodose; VXGy, volume receiving X Gy; DXcm 3, dose to X cm3 of the considered organ; GI, Gradient Index, volume encompassed by the 50% of the prescription isodose/prescription isodose volume; PCI, Paddick Conformity Index= (target volume in the prescription isodose)2/(target volume × prescription isodose volume).