Table 1.

Comparisons between different treatment groups for direct and indirect outcome measures.

Treatment comparison	Moderate or severe neuro-disability, or death		Moderate or severe neuro-disability		VP shunt or death		VP shunt		Death
	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p
Compared to Control
CSF removal	1.01 (0.86–1.19)	0.921	0.87 (0.45–1.70)	0.689	0.96 (0.8–1.15)	0.652	0.97 (0.75–1.24)	0.791	0.91 (0.53–1.57)	0.739
Diuretics	1.17 (0.99–1.39)	0.062	1.05 (0.47–2.34)	0.905	1.20 (0.93–1.54)	0.165	1.07 (0.79–1.44)	0.676	1.58 (0.81–3.08)	0.179
DRIFT	0.80 (0.53–1.22)	0.302	0.87 (0.35–2.17)	0.759	0.97 (0.62–1.53)	0.91	1.04 (0.6–1.79)	0.89	0.58 (0.15–2.28)	0.439
Early CSF removal					0.80 (0.47–1.37)	0.421	0.80 (0.39–1.67)	0.556	0.77 (0.26–2.32)	0.645
Fibrinolytics					1.20 (0.52–2.77)	0.675	1.41 (0.70–2.84)	0.342	1.26 (0.20–7.76)	0.806
Compared to CSF Removal
Diuretics	1.16 (0.92–1.47)	0.20	1.20 (0.42–3.42)	0.73	1.25 (0.91–1.70)	0.16	1.1 (0.75–1.63)	0.62	1.73 (0.73–4.10)	0.21
DRIFT	0.80 (0.51–1.24)	0.32	0.99 (0.32–3.09)	0.99	1.02 (0.62–1.65)	0.95	1.07 (0.59–1.96)	0.81	0.64 (0.15–2.78)	0.55
Early CSF removal					0.84 (0.51–1.39)	0.49	0.83 (0.42–1.65)	0.60	0.85 (0.33–2.20)	0.73
Fibrinolytics					1.25 (0.53–2.94)	0.61	1.45 (0.69–3.07)	0.33	1.38 (0.21–9.22)	0.74
Compared to Diuretic
DRIFT	0.69 (0.44–1.07)	0.10	0.82 (0.24–2.79)	0.76	0.81 (0.48–1.37)	0.44	0.97 (0.52–1.82)	0.94	0.37 (0.08–1.68)	0.20
Early CSF removal					1.49 (0.37–1.21)	0.19	0.75 (0.34–1.66)	0.48	0.49 (0.14–1.77)	0.28
Fibrinolytics					1.00 (0.45–2.23)	1.00	1.32 (0.64–2.71)	0.45	0.80 (0.13–4.91)	0.81
Compared to DRIFT
Early CSF removal					0.82 (0.41–1.66)	0.59	0.77 (0.31–1.92)	0.58	1.32 (0.23–7.59)	0.76
Fibrinolytics					1.23 (0.47–3.19)	0.67	1.35 (0.56–3.29)	0.51	2.15 (0.22–20.84)	0.51
Compared to Early CSF Removal
Fibrinolytics					1.49 (0.55–4.04)	0.43	1.75 (0.63–4.83)	0.28	1.63 (0.19–13.62)	0.65