Table 2.
Baseline clinical characteristics of patients
| Study | Study groups | Total number | Age | Male No. (%). | APACHE III score | Respiratory rate | PaO2/FiO2 | PEEP |
|---|---|---|---|---|---|---|---|---|
| Bernard 1987 | Steroid | 50 | 55 ± 2 | NA | NA | NA | NA | 8 ± 1 |
| Control | 49 | 56 ± 2 | NA | NA | NA | NA | 7 ± 1 | |
| Meduri 1998 | steroid | 16 | 47 ± 3.9 | 5 (31%) | 58(14) | NA | 161(14) | 12(1.2) |
| control | 8 | 51 ± 6.6 | 4 (50%) | 55(16) | NA | 141(19) | 14(1.7) | |
| Confalonieri 2005 | steroid | 23 | 60.4 ± 17.3 | 17 (74%) | 17.2 ± 4.1 | NA | 141 ± 49 | NA |
| control | 23 | 66.6 ± 14.7 | 15 (65%) | 18.2 ± 4 | NA | 178 ± 58 | NA | |
| Annane 2006 | steroid | 85 | 61 ± 16 | 56 (66 %) | NA | 18.5 ± 3 | 104 ± 42 | 6.8 ± 2.7 |
| control | 92 | 59 ± 18 | 65 (70%) | NA | 17.9 ± 3.1 | 108 ± 45 | 7.4 ± 3 | |
| Steinberg 2006 | steroid | 89 | 49 ± 19 | 40 (45%) | 87.6 ± 27.5 | NA | 126 ± 42 | 12.9 ± 5.6 |
| control | 91 | 49.2 ± 16.5 | 58 (64%) | 84.6 ± 29.4 | NA | 126 ± 40 | 12.3 ± 4.7 | |
| Meduri 2007 | steroid | 63 | 50.1 ± 15.3 | 34 (54%) | 60.2 ± 20.2 | NA | 118.4 ± 51.2 | 13 ± 5 |
| control | 28 | 53.2 ± 15.3 | 13 (46%) | 57.9 ± 21 | NA | 125.9 ± 38.6 | 11.2 ± 4 | |
| Tongyoo 2016 | steroid | 98 | 64.5 ± 17.3 | 50 (51%) | 21.7 ± 5.7 | NA | 175.4 ± 6.9 | 7.3 ± 3 |
| control | 99 | 64.3 ± 16 | 51 (52%) | 21.9 ± 5.7 | NA | 172.4 ± 6.7 | 6.8 ± 2.5 | |
| Villar 2020 | steroid | 139 | 56 ± 14 | 96 (69%) | NA | 23(5) | 142.4 ± 37.3) | 12.6 ± 2.7 |
| control | 138 | 58 ± 15 | 95 (69%) | NA | 23(5) | 143.5 ± 33.4 | 12.5 ± 2.6 |
Data are provided number and percent (%) or mean ± SD. PaO2 partial pressure pf arterial oxygen, PEEP positive end expiratory pressure, FiO2 fraction of inhaled oxygen, APACHE acute physiologic and chronic health evaluation