Table 4.
Univariate and multivariable logistic analysis for risks factors for liver injury in non-critically patients.
| Covariate | Univariate analysis | Multivariable analysis | ||
|---|---|---|---|---|
| OR | 95%CI | OR | 95%CI | |
| Demographics characteristics | ||||
| Age (year) | 0.982 | 0.953–1.012 | ||
| Female (n, %) | 0.629 | 0.287–1.359 | ||
| BMI (kg/m2) | 0.977 | 0.864–1.104 | ||
| Chronic medical illness (n, %) | 0.555 | 0.229–1.312 | ||
| Cardiovascular and cerebrovascular diseases (n, %) | 0.443 | 0.142–1.273 | ||
| Endocrine system disease (n, %) | 0.656 | 0.201–2.038 | ||
| Severe disease severity (n, %) | 1.198 | 0.507–2.868 | ||
| Treatment-related factors | ||||
| Treatment course of antivirus (day) | 1.043 | 0.956–1.142 | ||
| Lopinavir/ritonavir + arbidol (n, %) | 3.929 | 1.652–9.966 | 3.584 | 1.442–9.523 |
| Darunavir/cobicistat-based therapy (n, %) | 0.282 | 0.040–1.294 | ||
| Number of concomitant medications (number) | 1.118 | 1.020–1.236 | 1.121 | 1.049–1.212 |
| Glucocorticoids (n, %) | 1.222 | 0.554–2.719 | ||
| Quinolones (n, %) | 1.268 | 0.501–3.288 | ||
| NSAIDs (n, %) | 1.253 | 0.263–6.642 | ||
| Statins (n, %) | 0.296 | 0.014–2.396 | ||
| Immunosuppressive agents (n, %) | 1.885 | 0.175–41.310 | ||
| Laboratory results | ||||
| Normal Leucocytes (n,%) | 1.710 | 0.771–3.851 | ||
| Normal Neutrophils (n, %) | 1.046 | 0.470–2.337 | ||
| Normal lymphocytes (n, %) | 0.778 | 0.333–1.792 | ||
| Normal haemoglobin (n, %) | 0.916 | 0.275–2.963 | ||
| Normal platelets (n, %) | 2.035 | 0.575–8.208 | ||
| Normal serum creatinine (n, %) | 0.998 | 0.979–1.018 | ||
NSAIDs, Nonsteroidal anti-inflammatory drugs.