Table 1. A summary of the expression of mGluR6 outside the retina.

Location	Evidence	Tranduction	Function	Specie	Refs.
Cortical neurons/glial coltures Adult brain Microglia	mRNA mRNA and protein	- AC/cAMP - AC/cAMP	Neuroprotection + resting microglia and - activated microglia	Rat Rat	[23] [24]
Suprachiasmatic and arcuate nuclei of the hypothalamus Whole brain extract	mRNA			Rat	[28]
Brain: cortex, superior colliculus, corpus callosum, accessory olfactory bulb. Subcommissural organ cells Cornea (endothelium) Kidney (collecting tubules and vasa recta of inner medulla, parietal layer surrounding the glomerulus in the cortex) B-lymphocytes (spleen, germinal center of Peyer’s patches and ribcage bone marrow) Testis, conjunctiva, spinal cord, and eyelid	GFP under mGluR6 promoter mRNA	+ Ca2+ (L-AP4)	Secretion ?	Transgenic mouse	[9] [34]
Prostate (LNCaP androgen-dependent cells).	mRNA		Prostate cancer cell biology	Human	[33]
Bone marrow stromal cells	mRNA and protein	- Ca2+ influx and NO production	Regulation of bone matrix	Rat	[32]
Epidermal keratinocytes		CaM KII/ERK/MLC	Cytoskeletal reorganization Regulation of phagocytosis	Human	[42]
Melanocytes	mRNA and protein	Gαo (absent in melanocytes) restored TRPM1 inhibition	Melanin production	Human	[41]
Nodose ganglia and nucleus of the solitary tract	mRNA	- voltage-gated Ca2+ channels		Rats	[29, 30]
CA3 hippocampal slices	mRNA		Synaptic depression Down-regulated after status epilepticus		[31]

The expression of mRNA or protein, associated transduction mechanism, the function and specie are also indicated. + and - indicate stimulation or inhibition, respectively.