Table 2.
VMH simulation of tryptophan metabolism in intestinal flora
| Bacteria | Reactions | Score | Metabolites | ||
|---|---|---|---|---|---|
| Abbreviation | Description | Abbreviation | Description | ||
| Streptococcus | 5HLTDL | 5-Hydroxy-L-Tryptophan Decarboxy-Lyase | 4 | Trp-L 5htrp | L-Tryptophan 5-Hydroxy-L-tryptophan |
| LTDCL | L-Tryptophan Decarboxy-Lyase | 4 | |||
| 5HXKYNDCL | 5-Hydroxykynurenamine Decarboxy-Lyase | 1 | |||
| EX_5htrp(e) | Exchange of 5-Hydroxy-L-Tryptophan | 1 | |||
| EX_trp_L(e) | Exchange of L-Tryptophan | 1 | |||
| ACACT1r | Acetyl Coenzyme A C-Acetyltransferase | 0 | |||
| TRPt2r | L-tryptophan reversible transport via proton symport | 0 | |||
| Sutterella | FKYNH | N-Formyl-L-Kynurenine Amidohydrolase | 4 | Trp-L | L-Tryptophan |
| EX_trp_L(e) | Exchange of L-Tryptophan | 1 | |||
| TRPS1 | Tryptophan synthase (indoleglycerol phosphate) | 0 | |||
| TRPS2 | tryptophan synthase (indole) | 0 | |||
| TRPS3 | tryptophan synthase (indoleglycerol phosphate) | 0 | |||
| TRPt2r | L-tryptophan reversible transport via proton symport | 0 | |||
| Dorea | EX_trp_L(e) | Exchange of L-Tryptophan | 1 | Trp-L | L-Tryptophan |
| ANPRT | Anthranilate phosphoribosyltransferase | 0 | |||
| ANS | Anthranilate synthase | 0 | |||
| ANS2 | Anthranilate synthase 2 | 0 | |||
| IGPS | Indole-3-glycerol-phosphate synthase | 0 | |||
| PRAI | Phosphoribosylanthranilate isomerase | 0 | |||
| TRPS1 | Tryptophan synthase (indoleglycerol phosphate) | 0 | |||
| TRPS2 | tryptophan synthase (indole) | 0 | |||
| TRPS3 | tryptophan synthase (indoleglycerol phosphate) | 0 | |||
| TRPt2r | L-tryptophan reversible transport via proton symport | 0 | |||
| TRPTA | tryptophan transaminase | 0 | |||
| Lactobacillus | EX_trp_L(e) | Exchange of L-Tryptophan | 1 | Trp-L | L-Tryptophan |
| ACACT1r | Acetyl Coenzyme A C-Acetyltransferase | 0 | |||
| TRPt2r | L-tryptophan reversible transport via proton symport | 0 | |||
| Mycoplasma | EX_trp_L(e) | Exchange of L-Tryptophan | 1 | Trp-L | L-Tryptophan |
| TRPt2r | L-tryptophan reversible transport via proton symport | 0 | |||
| Adlercreutzia | EX_trp_L(e) | Exchange of L-Tryptophan | 1 | Trp-L | L-Tryptophan |
| TRPt2r | L-tryptophan reversible transport via proton symport | 0 | |||
| Paraprevotella | ANPRT | Anthranilate phosphoribosyltransferase | 0 | Trp-L | L-Tryptophan |
| ANS | Anthranilate synthase | 0 | |||
| ANS2 | Anthranilate synthase 2 | 0 | |||
| IGPS | Indole-3-glycerol-phosphate synthase | 0 | |||
| PRAI | Phosphoribosylanthranilate isomerase | 0 | |||
| TRPS1 | Tryptophan synthase (indoleglycerol phosphate) | 0 | |||
| TRPS2 | tryptophan synthase (indole) | 0 | |||
| TRPS3 | tryptophan synthase (indoleglycerol phosphate) | 0 | |||
| TRPTA | tryptophan transaminase | 0 | |||