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. 2020 Jun 29;13:84. doi: 10.1186/s13045-020-00922-1

Table 2.

Entry receptors for adenoviruses [37]

Receptor Ligand Reference
Primary receptors
 CXADR (coxsackie-adenovirus receptor) Ad5 knob (and other groups A, C, D, E, and F) [38]
 CD46 Ad3 knob (and other groups B and D) [39]
 Desmoglein-2 Ad3 knob (and other group B) [40, 41]
 CD80/CD86 Ad3 knob (and other group B) [33, 37]
Other receptors
 Cellular integrins Ad capsid (penton base) or Arg-Gly-Asp (RGD) modifications [42]
 Sialic acid Ad 37, 8, 19a (group D) [43]
 MHC-I (major histocompatibility complex class I) Ad5 [44]
 Vascular adhesion molecule 1 (VCAM-1) Ad5 [45]
 Heparan sulfate glycosaminoglycans (HS-GAGs) Ad5 [46]
 Dipalmitoyl phosphatidylcholine (DPPC) Ad5 hexon [47]
 Blood coagulation factor F(X) Ad 5 hexon [48, 49]