Table 2.
Entry receptors for adenoviruses [37]
Receptor | Ligand | Reference |
---|---|---|
Primary receptors | ||
CXADR (coxsackie-adenovirus receptor) | Ad5 knob (and other groups A, C, D, E, and F) | [38] |
CD46 | Ad3 knob (and other groups B and D) | [39] |
Desmoglein-2 | Ad3 knob (and other group B) | [40, 41] |
CD80/CD86 | Ad3 knob (and other group B) | [33, 37] |
Other receptors | ||
Cellular integrins | Ad capsid (penton base) or Arg-Gly-Asp (RGD) modifications | [42] |
Sialic acid | Ad 37, 8, 19a (group D) | [43] |
MHC-I (major histocompatibility complex class I) | Ad5 | [44] |
Vascular adhesion molecule 1 (VCAM-1) | Ad5 | [45] |
Heparan sulfate glycosaminoglycans (HS-GAGs) | Ad5 | [46] |
Dipalmitoyl phosphatidylcholine (DPPC) | Ad5 hexon | [47] |
Blood coagulation factor F(X) | Ad 5 hexon | [48, 49] |