Table 2.

The equations used to determine path structure features

Score description	Equation
The meta-path score is the product of all the edge weight scores from the start drug node to the ending target node in each path structure	$score\left(d_i,t_j,h,q\right)=\prod _{\forall e_x\in P_q}\left(w_x\right)$
The sum of all meta-path scores for each path structure (Sum feature)	$SumScore\left(d_i,t_j,h\right)=\sum _{\forall P_q\in R_{\mathit{ijh}}}score\left(d_i,t_j,h,q\right)$
The max path score is the highest meta-path score under each path structure (Max feature)	$MaxScore\left(d_i,t_j,h\right)=MA{X}_{\forall P_q\in R_{\mathit{ijh}}}\left(score\left(d_i,t_j,h,q\right)\right)$