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. 2020 Jun 30;21:48. doi: 10.1186/s40360-020-00427-0

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Effects of olanzapine, simvastatin treatment and simvastatin treatment combined with olanzapine on hepatic lipid levels. Hepatic mRNA expression of cholesterol biosynthesis and fatty acid synthesis-related genes: Srebp2 (a), Hmgcr (b), Hmgcs (c), Srebp1(d), Fasn (e) and Acc1 (f). g Lipid level of liver. The data from ORO staining. h Representative images of randomly selected sections of the liver stained for Oil red O in rats. Scale bars, 100 μm. Values are means ± SEM. *p < 0.05; **p < 0.01 vs. control; #p < 0.05, ##p < 0.01 vs. olanzapine-only group