Table 2.
MIC value distribution of Pasteurella multocida type B isolates derived from swine (n = 58)
| Break point | Ab | Number of isolates for each MIC (μg/mL) | MIC50 | MIC90 | %R | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ≤0.03 | 0.06 | 0.125 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | ≥16 | |||||
| ≥1 | ENR | 45 | 2 | 2 | 1 | 4 | 3 | 0 | 1 | 0 | 0 | ≤0.03 | 0.5 | 6.9 |
| ≥8 | CEF | 39 | 3 | 0 | 1 | 4 | 7 | 3 | 1 | 0 | 0 | ≤0.03 | 1 | 0 |
| > 8 | GEN | 0 | 0 | 0 | 0 | 0 | 3 | 11 | 16 | 19 | 9 | 4 | ≥16 | 15.5 |
| ≥32 | C | 0 | 0 | 0 | 2 | 29 | 6 | 3 | 3 | 4 | >11c | 0.5 | ≥16 | 17.2 |
| > 2 | LIN | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 52 | ≥16 | ≥16 | 100 |
| ≥1 | PEN | 10 | 12 | 17 | 3 | 0 | 0 | 16 | 0 | 0 | 0 | 0.125 | 2 | 27.6 |
| ≥2a | OXY | 4 | 3 | 6 | 26 | 6 | 1 | 2 | 1 | 9 | 0 | 0.25 | 8 | 20.7 |
| ≥2 | TE | 3 | 0 | 6 | 16 | 9 | 7 | 7 | 3 | 7 | 0 | 0.5 | 8 | 29.3 |
| ND | ERY | 0 | 0 | 2 | 2 | 3 | 8 | 1 | 8 | 0 | 34 | ≥16 | ≥16 | ND |
| NDb | NEO | 0 | 0 | 0 | 0 | 0 | 1 | 6 | 14 | 20 | 17 | 8 | ≥16 | ND |
a breakpoint reference value for tetracycline; b breakpoint value for P. multocida derived from dogs; c MIC value = 32 μg/mL. Ab Antibiotic; C Chloramphenicol; CEF Ceftiofur; ENR Enrofloxacin; ERY Erythromycin; GEN Gentamicin; LIN Lincomycin; MIC Minimum inhibitory concentration; ND Non-determined value for P. multocida according to the Clinical and Laboratory Standards Institute (CLSI; 2013); NEO Neomycin; OXY Oxytetracycline; PEN Penicillin; TE Tetracycline