Table 3.
Adverse events
| Possibly related to study drug | |
|---|---|
| Event | No. of participants (%) |
| Transient paresthesias in groin and lower extremities | 5 (62.5) |
| Transient increase in lower extremity spasticity | 1 (12.5) |
| Transient lower extremity weakness | 1 (12.5) |
| Worsened fatigue | 2 (25) |
| Fever and rigors | 1 (12.5) |
| Unrelated to study drug | |
| Event | No. of participants (%) |
| Post-lumbar puncture headache | 2 (25) |
| Disorientation and drowsiness# | 1 (12.5) |
Following administration of lorazepam for transient worsening of lower extremity spasticity