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. 2020 Jun 23;14:656. doi: 10.3389/fnins.2020.00656

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Copyright © 2020 Palfi, Yesmambetov, Humphries, Hokamp and Farrar.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Inner plexiform layer (IPL) and ganglion cells. Retinas from wt, Tulp1-/-, Rho-/-, and Rds-/- mice were taken at p5, p8, and p14 (n = 5–6). (a–l) Sections were co-labeled with MAP2 (left; green) and CTBP2 (RYBEYE; right; purple) immunocytochemistries. MAP2 (n = 3; m) and CTBP2 (n = 3; n) label intensities in the inner plexiform layer (IPL) were quantified from microscope images using cellSens software and results are given in bar charts; bars represent mean + SD. INL, inner nuclear layer; NBL, neuroblast layer. Scale bar (l): 20 mm. *p < 0.05; **p < 0.01; ***p < 0.001 (ANOVA). Black stars above bars refer to differences between IRD and wt mice, purple stars above bars refer to differences between Tulp1-/- and the other IRD mice; black stars within bars refer to a difference compared to the previous time point.