. 2019 May 11;221(4):510–515. doi: 10.1093/infdis/jiz254

Table 1.

Relationships Between Anti-inflammatory and Proinflammatory Markers and Coronary Plaque in Persons With Human Immunodeficiency Virus

	All PWH (n = 144)		Virally Suppressed PWH Receiving ART (n = 120)
Relationships of Anti-inflammatory and Proinflammatory Markers with Number of Coronary Segments Containing Plaque	Spearman ρ	P Value	Spearman ρ	P Value
Anti-inflammatory markers
IL-10
Noncalcified plaque	−0.24	.004^a	−0.20	.03^a
Calcified plaque	−0.01	.90	−0.01	.90
Total plaque	−0.19	.02^a	−0.18	.06
Proinflammatory markers
sCD163
Noncalcified plaque	0.19	.02^a	0.24	.009^a
Calcified plaque	0.08	.35	0.06	.50
Total plaque	0.11	.17	0.18	.06
CCL2
Noncalcified plaque	0.10	.23	0.11	.24
Calcified plaque	0.12	.16	0.10	.27
Total plaque	0.22	.01^a	0.21	.02^a
hsIL-6
Noncalcified plaque	0.09	.31	0.18	.07
Calcified plaque	˗0.06	.52	−0.03	.77
Total plaque	0.06	.51	0.18	.07
hsCRP
Noncalcified plaque	−0.06	.51	0.02	.86
Calcified plaque	−0.04	.67	0.002	.98
Total plaque	0.01	.88	0.09	.33

Abbreviations: ART, antiretroviral therapy; CCL2, C-C motif chemokine ligand 2; hsCRP, high-sensitivity C-reactive protein; hsIL-6, high-sensitivity interleukin 6; IL-10, interleukin 10; PWH, persons with human immunodeficiency virus; sCD163, soluble CD163.

^aSignificant at P <.05.