Graphs show receiver operating characteristic (ROC) analysis of liver fibrosis staging by (a) type 1 collagen MRI with EP-3533, (b) oxidized collagen MRI with Gd-Hyd, (c) shear stiffness with MR elastography, and (d) native T1 over collagen proportionate area (CPA) values. ROC curves were grouped to assess ability of each imaging technique to distinguish nonfibrotic group (CPA ≤4.8%) from fibrotic groups (CPA >4.8%) and to distinguish no disease or moderate fibrosis (CPA ≤10.3%) from severe fibrosis (CPA >10.3%). Area under ROC curve (AUROC), 95% confidence interval (CI), and P value are given for each curve.